BRICHOS - a superfamily of multidomain proteins with diverse functions

BMC Research Notes

Table 2 Conservation measures in the hydrophobic region

Family	n	*cscore*	ID	GC
ITM2A	8	92	82	86
ITM2B	13	93	80	64
ITM2C	16	79	50	36
Group A	9	66	26	28
GKN1	11	69	38	25
GKN2	8	77	42	26
TNMD	5	72	44	41
LECT1	13	84	74	49
group C	11	70	50	17
proSP-C	12	96	96	91

Conservation the hydrophobic region for the different BRICHOS families, shown in percent. cscore denotes average conservation score. ID denotes median pairwise sequence identity. GC denotes the proportion of positions conserved either strictly or within the groups of highly similar residues {DE}, {KR}, {FILMV} or {ST}. n denotes the number of sequences present in the underlying set. GC is a stricter measure of functional conservation, but may be more sensitive to atypical sequences.

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