Figure 1

Differential gene expression results. Venn diagrams show the overlap between different gene selection criteria (Info and SAM P < 0.05 and Fold difference > 1.2) for (A) PBMC, (B) pFC, (C) Hic and (D) Hyp. This gene selection strategy significantly reduced the number of genes identified as DE by any one single criterion. Also shown are the false colour sample profiles of hierarchically clustered differentially expressed genes for (E) PBMC samples [347 over- and 71 under-expressed], and neural tissues (F) pFC [66 over- and 88 under-expressed], (G) Hic [71 over- and 75 under-expressed] and (H) Hyp [69 over- and 81 under-expressed]. The selected genes produce a clear separation between MS and SH samples. Genes more highly expressed in MS samples are at the top and those more highly expressed in SH samples at the bottom. P = PBMC; F = pFC.