Figure 3

Aggrecanase-derived aggrecan fragments released during the early, mid and late phase of cartilage explants stimulated with catabolic cytokines. As for figure 2, but release of fragments in the early (day 2-7, black bar), mid phase (day 9-14, dark grey bar) and late phase (day 16-21, light grey bar) are expressed in percentage of accumulated release during the 21 day study period.