TY - JOUR AU - de Souza, Ana HA AU - Cabral, Lucio M. AU - Huf, Gisele PY - 2009 DA - 2009/03/02 TI - Current practices in the use of sildenafil for pulmonary arterial hypertension in Brazilian hospitals JO - BMC Research Notes SP - 30 VL - 2 IS - 1 AB - Sildenafil is a cyclic guanosine monophosphate-specific phosphodiesterase-5 inhibitor used for treating pulmonary hypertension. Although the use of sildenafil in patients under 18 years old is off-label, this inhibitor has been widely prescribed for children treatment at hospitals in Brazil. In this work we evaluated the current practices in using sildenafil in the three main reference hospitals of Rio de Janeiro to design a clinical trial. Then we analyzed the content of sildenafil in powder paper preparations used in these institutions. SN - 1756-0500 UR - https://doi.org/10.1186/1756-0500-2-30 DO - 10.1186/1756-0500-2-30 ID - de Souza2009 ER -