TY - JOUR AU - Vandamme, Drieke AU - Lambert, Ellen AU - Waterschoot, Davy AU - Tondeleir, Davina AU - Vandekerckhove, Joël AU - Machesky, Laura M. AU - Constantin, Bruno AU - Rommelaere, Heidi AU - Ampe, Christophe PY - 2009 DA - 2009/03/10 TI - Phenotypes induced by NM causing α-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes JO - BMC Research Notes SP - 40 VL - 2 IS - 1 AB - Nemaline myopathy is a neuromuscular disorder characterized by the presence of nemaline bodies in patient muscles. 20% of the cases are associated with α-skeletal muscle actin mutations. We previously showed that actin mutations can cause four different biochemical phenotypes and that expression of NM associated actin mutants in fibroblasts, myoblasts and myotubes induces a range of cellular defects. SN - 1756-0500 UR - https://doi.org/10.1186/1756-0500-2-40 DO - 10.1186/1756-0500-2-40 ID - Vandamme2009 ER -