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Table 5 Characteristics of anti-CCP-positive and -negative PsA patients

From: Assessment of anti-cyclic citrullinated peptide in psoriatic arthritis

  Anti-CCP-positive (n = 7) Anti-CCP-negative (n = 33) P-value
Age (years)    
Mean ± SD (range) 43 ± 5.7 (39–50) 47 ± 6.9 (33–54) 0.161*
Sex    
Male n (%) 3 (42.86%) 15 (45.45%)  
female n (%) 4 (57.14%) 18 (54.55%) 0.67**
Disease Duration (months)    
Mean ± SD (range) 40.7 ± 12.34 (30–54) 37 ± 9 (24–60) 0.36*
PASI    
Mean ± SD (range) 10 ± 1.53 (8–11) 8.86 ± 1.9 (7–13) 0.146*
Psoriatic nail changes    
n (%) 4 (57.14%) 29 (87.9%) 0.087**
Involved joints    
median (range) 15 (10–24) 6 (5–10) 0.0135*
Swollen joints    
median (range) 2.5 (2–7) 1 (0–2) 0.023*
Tender joints    
median (range) 9 (3–16) 3 (0–8) 0.009*
Spondyloarthritis    
n (%) 1 (14.28%) 5 (15.15%) 0.901**
Oligoarthritis    
n (%) 0 6 (18.18%) 0.567**
Symmetric Polyarthritis    
n (%) 7 (100%) 12 (36.36%) 0.003**
Asymmetric Polyarthritis    
n (%) 0 2 (6.06%) 0.542**
Deformities of peripheral joints    
n (%) 7 (100%) 15 (45.45%) 0.011**
Functional impairment of peripheral joints    
n (%) 7 (100%) 15 (45.45%) 0.011**
Radiological changes: peripheral deformities/erosions    
n (%) 7 (100%) 15 (45.45%) 0.011**
RF concentrations (IU/ml)    
Median (range) 15 (7–30) 9 (4–33) 0.0714*
Anti-CCP concentrations (U/ml) Mean ± SD (range) 34.7 ± 8 (30–45) 3.21 ± 1.16 (1–5) 0.0001*
  1. * Student's t and Mann Whitney tests.
  2. ** Chi-square and Fisher's exact tests