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Table 1 Effect of Losartan on several markers of the OLETF rats

From: Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat

  OLETF OLETF+Losartan
Body weight (g) 671.3 ± 35.2 662 ± 41.1
Liver weight (g) 25.8 ± 4.3 22.4 ± 4.0
Glucose (mg/dl) 271.3 ± 41.0 262.0 ± 36.8
Insulin (nM/ml) 128.0 ± 10.4 117.2 ± 9.6
ALT (IU/l/dl) 102.4 ± 17.8 96.7 ± 16.6
Total bilirubin (mg/dl) 0.11 ± 0.07 0.14 ± 0.08
Total cholesterol (nmol/l) 1.04 ± 0.12 0.93 ± 0.11
TGF-β (ng/mg liver) 56.6 ± 14.3 34.3 ± 10.1*
  1. Results are expressed as means ± SD
  2. *: Statistically significant diferences as compared with OLETF-control group