Table 1 Effect of Losartan on several markers of the OLETF rats

Body weight (g)

671.3 ± 35.2

662 ± 41.1

Liver weight (g)

25.8 ± 4.3

22.4 ± 4.0

Glucose (mg/dl)

271.3 ± 41.0

262.0 ± 36.8

Insulin (nM/ml)

128.0 ± 10.4

117.2 ± 9.6

ALT (IU/l/dl)

102.4 ± 17.8

96.7 ± 16.6

Total bilirubin (mg/dl)

0.11 ± 0.07

0.14 ± 0.08

Total cholesterol (nmol/l)

1.04 ± 0.12

0.93 ± 0.11

TGF-β (ng/mg liver)

56.6 ± 14.3

34.3 ± 10.1*