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Table 3 Biomarkers of lipid peroxidation, antioxidant status, inflammation, insulinaemia and endothelial dysfunction in RA patients and controls.

From: Biomarkers of oxidant stress, insulin sensitivity and endothelial activation in rheumatoid arthritis: a cross-sectional study of their association with accelerated atherosclerosis

marker controls RA patients p value
8-IP 0.659 (0.449–0.845) 0.925 (0.598–1.248) 0.004
MDA 3.195 (2.825–3.434) 2.900 (2.648–3.346) ns
selenium 91.14 (84.12–101.3) 84.55 (77.18–91.08) 0.003
TAC (ws) 730.0 (586.9–888.0) 728.2 (532.5–905.9) ns
TAC (pfs) 343.7 (292.2–394.9) 334.7 (262.9–426.0) ns
vitamin A 2.714 (2.472–3.191) 2.615 (2.241–3.224) ns
vitamin E 13.63 (11.91–16.53) 13.41 (12.40–15.27) ns
CRP 3.025 (1.269–5.246) 9.335 (5.201–11.79) < 0.001
IL-6 0.046 (0–0.398) 3.723 (1.773–11.25) < 0.001
insulin 6.65 (4.4–8.9) 7.65 (5.9–11.4) 0.035
glucose 4.700 (4.5–5.0) 4.700 (4.4–5.1) ns
HOMA-S 0.718 (0.54–1.08) 0.615 (0.40–0.80) 0.039
adiponectin 3.369 (2.31–4.74) 4.543 (3.15–6.97) 0.012
VCAM 241.1 (200.4–260.8) 253.8 (224.7–298.0) 0.029
E-selectin 86.74 (54.19–107.3) 113.4 (86.74–113.4) < 0.001
P-selectin 17.34 (14.49–23.62) 20.29 (16.47–25.40) ns
  1. Results are expressed as median (interquartile range). The Mann-Whitney U test was used to calculate significance between groups. ns = not significant. Units were expressed as follows: 8-IP as ng/g creatinine; MDA and vitamin A as μmol/l; selenium, VCAM, E-selectin and P-selectin as μg/l; TAC (ws and pfs) as mmol/l trolox equivalents; vitamin E, CRP and adiponectin as mg/l; IL-6 as ng/l; insulin as mU/l; glucose as mmol/l.