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Table 3 Biomarkers of lipid peroxidation, antioxidant status, inflammation, insulinaemia and endothelial dysfunction in RA patients and controls.

From: Biomarkers of oxidant stress, insulin sensitivity and endothelial activation in rheumatoid arthritis: a cross-sectional study of their association with accelerated atherosclerosis

marker

controls

RA patients

p value

8-IP

0.659 (0.449–0.845)

0.925 (0.598–1.248)

0.004

MDA

3.195 (2.825–3.434)

2.900 (2.648–3.346)

ns

selenium

91.14 (84.12–101.3)

84.55 (77.18–91.08)

0.003

TAC (ws)

730.0 (586.9–888.0)

728.2 (532.5–905.9)

ns

TAC (pfs)

343.7 (292.2–394.9)

334.7 (262.9–426.0)

ns

vitamin A

2.714 (2.472–3.191)

2.615 (2.241–3.224)

ns

vitamin E

13.63 (11.91–16.53)

13.41 (12.40–15.27)

ns

CRP

3.025 (1.269–5.246)

9.335 (5.201–11.79)

< 0.001

IL-6

0.046 (0–0.398)

3.723 (1.773–11.25)

< 0.001

insulin

6.65 (4.4–8.9)

7.65 (5.9–11.4)

0.035

glucose

4.700 (4.5–5.0)

4.700 (4.4–5.1)

ns

HOMA-S

0.718 (0.54–1.08)

0.615 (0.40–0.80)

0.039

adiponectin

3.369 (2.31–4.74)

4.543 (3.15–6.97)

0.012

VCAM

241.1 (200.4–260.8)

253.8 (224.7–298.0)

0.029

E-selectin

86.74 (54.19–107.3)

113.4 (86.74–113.4)

< 0.001

P-selectin

17.34 (14.49–23.62)

20.29 (16.47–25.40)

ns

  1. Results are expressed as median (interquartile range). The Mann-Whitney U test was used to calculate significance between groups. ns = not significant. Units were expressed as follows: 8-IP as ng/g creatinine; MDA and vitamin A as μmol/l; selenium, VCAM, E-selectin and P-selectin as μg/l; TAC (ws and pfs) as mmol/l trolox equivalents; vitamin E, CRP and adiponectin as mg/l; IL-6 as ng/l; insulin as mU/l; glucose as mmol/l.