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Table 5 Univariate logistic regression of factors associated with carotid plaque in RA patients and controls

From: Biomarkers of oxidant stress, insulin sensitivity and endothelial activation in rheumatoid arthritis: a cross-sectional study of their association with accelerated atherosclerosis

  controls RA patients
variable odds ratio ROC p value odds ratio ROC p value
age 1.22 (1.04–1.42) 0.79 0.013 1.11 (1.01–1.22) 0.68 0.034
IMT 2.79 (1.32–5.91) 0.78 0.008 1.34 (0.77–2.36) 0.59 0.300
VCAM 1.02 (1.01–1.04) 0.77 0.007 1.00 (0.99–1.01) 0.62 0.375
SBP 1.05 (1.01–1.10) 0.76 0.014 1.04 (0.99–1.08) 0.61 0.063
smoking 1.09 (1.02–1.17) 0.74 0.010 1.05 (0.99–1.11) 0.61 0.109
IL-6 1.74 (0.88–3.43) 0.71 0.110 0.97 (0.91–1.04) 0.52 0.449
E-selectin 1.02 (1.00–1.04) 0.71 0.055 1.00 (0.99–1.01) 0.49 0.809
8-IP 3.83 (0.86–17.0) 0.69 0.077 1.01 (0.49–2.08) 0.48 0.972
LDL 1.76 (0.92–3.34) 0.67 0.086 1.34 (0.68–2.66) 0.56 0.394
adiponectin 1.27 (0.98–1.65) 0.66 0.066 1.08 (0.88–1.33) 0.62 0.436
insulin 1.17 (0.98–1.40) 0.63 0.088 1.00 (0.91–1.10) 0.50 0.980
selenium 0.98 (0.93–1.03) 0.61 0.365 0.98 (0.94–1.02) 0.58 0.296
BMI 1.05 (0.96–1.15) 0.58 0.319 0.95 (0.85–1.07) 0.54 0.431
CRP 1.07 (0.93–1.23) 0.56 0.358 1.00 (0.96–1.05) 0.53 0.884
  1. Odds ratio (95% confidence interval), area under the receiver operating characteristic (ROC) curve and p value using a univariate logistic regression model with occurrence of carotid plaque (0 or 1) in subjects as the response.