Table 4 Performance characteristics of the IGRA-methods.
From: IGRA tests perform similarly to TST but cause no adverse reactions: pediatric experience in Finland
Parameter | Sensitivity (95% CI§) | Specificity 95% CI) | PPV† (95% CI) | NPV‡ (95% CI) | Accuracy (95% CI) |
|---|---|---|---|---|---|
Method | |||||
Ly-TbSpot | 0.85 | 1.00 | 1.00 | 0.96 | 0.96 |
n = 72 | (0.64 – 0.95) | (0.93 – 1.00) | (0.82 – 1.00) | (0.87 – 0.99) | (0.88 – 0.99) |
B-TbIFNγ | 0.92 | 0.91 | 1.00 | 0.96 | 0.91 |
n = 41 | (0.67 – 0.99) | (0.77 – 0.97) | (0.76 – 1.00) | (0.84 – 0.99) | (0.80 – 0.97) |