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Table 4 Performance characteristics of the IGRA-methods.

From: IGRA tests perform similarly to TST but cause no adverse reactions: pediatric experience in Finland

Parameter Sensitivity (95% CI§) Specificity 95% CI) PPV (95% CI) NPV (95% CI) Accuracy (95% CI)
Method      
Ly-TbSpot 0.85 1.00 1.00 0.96 0.96
n = 72 (0.64 – 0.95) (0.93 – 1.00) (0.82 – 1.00) (0.87 – 0.99) (0.88 – 0.99)
B-TbIFNγ 0.92 0.91 1.00 0.96 0.91
n = 41 (0.67 – 0.99) (0.77 – 0.97) (0.76 – 1.00) (0.84 – 0.99) (0.80 – 0.97)
  1. * Pre-test probability, † Positive predictive value, ‡ Negative predictive value, §Confidence interval.