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Table 3 Odds Ratios (OR) and 95% Confidence Intervals (CI) for Preeclampsia (PE) and gestational diabetes mellitus (GDM) according to Tertiles of Maternal Blood DNA Telomere Length Sampled at Delivery, Seattle, Washington, 1998-2002.

From: Telomere length, pre-eclampsia, and gestational diabetes

Telomere length

Preeclampsia (N = 50)

Controls

Unadjusted OR

Age-adjusted OR

Adjusted OR*

  

(N = 50)

(95%CI)

(95%CI)

(95%CI)

Tertile 1 (<0.720)

23

19

1.00 (reference)

1.00 (reference)

1.00 (reference)

Tertile 2 (0.720-0.800)

8

15

0.44 (0.15-1.26)

0.45 (0.15-1.35)

0.46 (0.62-3.38)

Tertile 3 (≥ 0.801)

19

16

0.98 (0.40-2.41)

1.08 (0.42-2.75)

0.92 (0.15-5.46)

P for trend

  

0.91

0.94

0.83

Telomere length

GDM

Controls

Unadjusted OR

Age-Adjusted OR

Adjusted OR*

 

(N = 25)

(N = 50)

(95%CI)

(95%CI)

(95%CI)

Tertile 1 (<0.720)

14

19

1.00 (reference)

1.00 (reference)

1.00 (reference)

Tertile 2 (0.720-0.800)

6

15

0.54 (0.17-1.75)

0.56 (0.17-1.87)

0.96 (0.19-4.77)

Tertile 3 (≥ 0.801)

5

16

0.42 (0.13-1.43)

0.35 (0.10-1.23)

0.65 (0.13-3.34)

P for trend

  

0.15

0.09

0.61

  1. The cutoffs of tertile were based on the distribution in controls
  2. * adjusted for maternal age, pre-pregnancy body mass index, gestational age at delivery and time from last meal to blood draw.