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Table 1 False positive rate of different methods on a null simulation.

From: AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm

 

False positive rate

    

AntEpiSeeker

P value threshold

Exhaustive search

BEAM

SNPHarvester

Before minimizing false positives

After minimizing false positives

10-5

5.5 × 10-6

No positives reported

1.4 × 10-2

3.5 × 10-6

3.0 × 10-6

10-4

5.3 × 10-5

No positives reported

1.6 × 10-2

3.0 × 10-5

1.1 × 10-5

10-3

6.9 × 10-4

No positives reported

2.0 × 10-2

2.9 × 10-4

3.7 × 10-5

10-2

8.4 × 10-3

No positives reported

2.4 × 10-2

2.0 × 10-3

6.6 × 10-5