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Table 3 Some epistatic interactions identified by AntEpiSeeker on WTCCC RA data.

From: AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm

Epistatic interactions Location Related genes P value
(rs6457617, rs41443144) 6p21.32-6p25.1 MHC, RP3 <10-16
(rs743777, rs9627642) 22q12.3-22q13.31 NR, NR < 10-16
(rs2837960, rs41492246) 21q22.3-21q22.12 NR, NR < 10-16
(rs6920220, rs17165379) 6q23.3-6p25.3 TNFAIP3, NR < 10-16
(rs6457620, rs41454544) 6p21.32-6q21 HLA-DRB1, OSTM1 < 10-16
(rs3890745, rs41348151) 1p36.32-1p21.3 MMEL1, NR < 10-16
(rs4810485, rs2748666) 20q13.12-20q11.23 CD40, NR < 10-16