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Table 4 Comparison of the EF hands in zebrafish and human CaBPs and calneurons.

From: Bioinformatic analysis of CaBP/calneuron proteins reveals a family of highly conserved vertebrate Ca2+-binding proteins

  EF1 EF2 EF3 EF4
  Zebrafish Human Conserved Zebrafish Human Conserved Zebrafish Human Conserved Zebrafish Human Conserved
CaBP1 D D 75% D D 92% (N) E E 83% E E 92%
CaBP2 D E 50% D D 78% (N) E E 67% E E 100%
CaBP4 D E 42% D E 58% (N) E E 67% E E 92%
CaBP5 D D 58% D D 83% (N) E E 58% E E 92%
Calneuron 1 E E 100% E E 100% E E 100% (N) E E 92% (N)
Calneuron 2 E E 100% E E 100% E E 100% (N) I D 58% (N)
  1. The table indicates whether the amino acid at position 12 of the EF-hand Ca2+-coordinating loop is an aspartic acid (D) or glutamate (E) and the percentage sequence identity between zebrafish and human EF-hand loop sequences. In the conserved column it is also indicated if the EF hand is predicted to be non-functional (N) and these are the same in the human and zebrafish proteins.