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Table 1 Gene information on experimental verified splice variants.

From: A study of alternative splicing in the pig

 

Gene

Tissue-specificity

No.

Symbol

Name

Function

EST

qPCR

P -value

4

IGF2

insulin-like growth factor 2 (somatomedin A)

Cell proliferation

Liver

Liver

5.5 × 10-27

7

EIF4E2

eukaryotic translation initiation factor 4E family member 2

Translation

Intestine

Intestine/lymph

2.6 × 10-44

14

RBM4

RNA binding motif protein 4

Transcription

Thymus

Brain

Brain*

7.2 × 10-36

1.9 × 10-9

15

ANAPC11

anaphase promoting complex subunit 11 homolog (yeast)

Cell cycle

Muscle, Lymph - Brain - Intestine

Liver

9.7 × 10-5

27

ATP5S

ATP synthase, H+ trans-porting, mitochondrial F0 complex, subunit s (factor B)

Ion transporter

Muscle

Muscle

5.7 × 10-18

28

HNRPLL

heterogeneous nuclear ribonucleoprotein L-like

RNA processing

Brain

Brain*

1.0 × 10-21

41

PPP3CC

protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform

Phophatase

Brain

Muscle*

2.1 × 10-42

71

CEP27

centrosomal protein 27 kDa

Centrosome

Brain

Brain

7.8 × 10-18

3.3 × 10-15

85

BSCL2

Bernardinelli-Seip congenital lipodystrophy 2 (seipin)

unknown

Ovary

Ovary*

1.7 × 10-30

97

AUH

AU RNA binding protein/enoyl-Coenzyme A hydratase

RNA catabolism

Heart

Heart*

Ovary

2.0 × 10-19

4.0 × 10-16

  1. No. refers to the ranking on the predicted tissue-specific list (Additional File 2). Tissue specificity is listed both in regard to the in silico predictions (manual inspection of EST data) and in regard to the experimental verifications (qPCR). The P-value is referring to the ANOVA results. Tissues marked with * are not exclusive tissue-specific but tissue-specific ratios between the splice variants have been detected.