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Table 1 Internal Repeats in CDF carrier and CRAC channel proteins.

From: Animal Ca2+ release-activated Ca2+ (CRAC) channels appear to be homologous to and derived from the ubiquitous cation diffusion facilitators

A. Comparison of CDF 2TMS segments

    

TMS # of

TMS # of

No. of Residues

Comparison

%

%

No. of

CDF proteins

CDF proteins

Compared

score (SD)

Identity

Similarity

Gaps

1 and 2

3 and 4

58

12.2

28.6

44.6

1

3 and 4

5 and 6

65

11.0

36.7

48.3

2

1 and 2

5 and 6

55

9.0

28.6

35.7

1

B. Comparison of CDF 2TMS segments with Orai 2TMS segments

   

TMS # of

TMS # of

No. of Residues

Comparison

%

%

No. of

CDF proteins

Orai proteins

Compared

score (SD)

Identity

Similarity

Gaps

3 and 4

1 and 2

72

14.6

36.4

51.5

2

5 and 6

3 and 4

55

8.6

33.3

48.1

1

3 and 4

3 and 4

80

6.5

29.8

35.1

1

5 and 6

1 and 2

70

2.4

26.5

26.5

0

1 and 2

1 and 2

26

2.3

46.1

53.8

1

1 and 2

3 and 4

33

-0.1

20.0

26.7

0