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Table 2 KCN inhibition of rate of peroxidation of unbound UCB by HRP (Kp)

From: Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver

Relative Kpa
  vs control vs LMbor BMc
Control (n = 18) 100 ± 3.1  
0.5 mM KCN (n = 12) 84.7 ± 5.8 (p < 0.001)  
1.0 mM KCN (n = 11) 73.4 ± 5.8 (p < 0.001)  
BMb(n = 11) 99.2 ± 4.4 (p = 0.618)  
0.5 mM KCN (n = 6) 88.7 ± 3.3 (p < 0.001) 89.4 ± 3.4 (p < 0.001)
1.0 mM KCN (n = 6) 72.1 ± 6.8 (p < 0.001) 72.1 ± 6.9 (p < 0.001)
LMc(n = 12) 172 ± 6.2 (p < 0.001)  
0.5 mM KCN (n = 6) 102 ± 8.1 (p = 0.580) 59.4 ± 4.7 (p < 0.001)
1.0 mM KCN (n = 6) 83.8 ± 9.3 (p < 0.001) 48.8 ± 5.4 (p < 0.001)
  1. aPercent of Kp values normalized to control (no mitochondria); bBM, mouse brain mitochondria; cLM, mouse liver mitochondria.