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Table 1 Number of adverse drug reactions reported for psychotropic medication in the paediatric population by age and seriousness (in italic) (1998 to 2007)

From: Adverse drug reactions from psychotropic medicines in the paediatric population: analysis of reports to the Danish Medicines Agency over a decade

Age groups (years) <1 1<2 2-10 11<17 Total
Antipsychotics (N05A)      
Levomepromazine 1 (1) 0 0 1 2 (1)
Zipradison 0 0 2 16 (11) 18 (11)
Zuclopenthixol 1 (1) 0 0 1 (1) 2 (2)
Chlorprothixene 0 0 0 2 2
Clozapine 0 0 0 1 1
Olanzapine 8 (8) 5 (5) 0 11 (3) 24 (16)
Quetiapine 1 (1) 0 1 (1) 14 (12) 16 (14)
Sulpiride 0 0 0 3 3
Risperidone 1 (1) 0 5 18 (5) 24 (6)
Aripiprazol 0 0 0 14 (3) 14 (3)
Total 12 (12) 5 (5) 8 (1) 81 (35) 106 (53)
Hypnotics and sedatives (N05B/N05C)      
Diazepam 1 (1) 0 0 0 1 (1)
Oxazepam 3 (3) 0 0 0 3 (3)
Buspirone 1 (1) 0 0 0 1 (1)
Chloral hydrate 0 0 3 (3) 0 3 (3)
Midazolam 0 0 1 (1) 2 (2) 3 (3)
Total 5 (5) 0 4 (4) 2 (2) 11 (11)
Antidepressants (N06A)      
Imipramine 0 0 1 (1) 0 1 (1)
Clomipramine 1 (1) 0 0 0 1 (1)
Amitriptyline 2 (2) 0 0 0 2 (2)
Fluoxetine 14 (14) 0 0 1 (1) 15 (15)
Citalopram 17 (17) 4 (4) 5 (2) 10 (6) 36 (29)
Paroxetine 5 (4) 0 0 6 (2) 11 (6)
Sertralin 11 (11) 0 9 (3) 25 (20) 45 (34)
Escitalopram 1 (1) 1 (1) 0 0 2 (2)
Oxitriptan 0 0 0 3 3
Mirtazapin 1 (1) 0 0 12 (8) 13 (9)
Venlafaxin 1 (1) 0 0 3 4 (1)
Total 53 (52) 5 (5) 15 (6) 60 (37) 133 (100)
Psychostimulants (N06B)      
Methylphenidate 0 0 85 (35) 44 (17) 129 (52)
Modafinil 0 0 0 7 (7) 7 (7)
Atomoxetine 0 0 23 (7) 20 (11) 43 (18)
Total 0 0 108 (42) 71 (35) 179 (77)
Total N05 and N06 70 (69) 10 (10) 135 (53) 214 (109) 429 (241)