Skip to main content

Table 2 Serum bone metabolic markers over the study period for spring water and magnesium bicarbonate (supplemented) spring water groups

From: A double-blind, placebo-controlled study of the short term effects of a spring water supplemented with magnesium bicarbonate on acid/base balance, bone metabolism and cardiovascular risk factors in postmenopausal women

   Spring Water (n = 33) Supplemented Spring Water (n = 34)
  Visit Day 0 Day 84 Day 0 Day 84
Parathyroid Hormone (pmol/L) Mean (SD) 3.85 (1.79) 4.57 (2.14) 4.24 (1.74) 4.21 (1.96)
  Change from baseline (Day 0) (SD)   0.72 (1.52)   -0.02 (1.65)
  *P value    0.369 0.059
1,25dihydroxyvitamin D (pmol/L) Mean (SD) 120.8 (40.9) 126.8 (40.4) 118.7 (39.8) 124.3 (40.7)
  Change from baseline (Day 0) (SD)   7.1 (49.1)   5.6 (47.9)
  *P value    0.835 0.766
Osteocalcin Mean (SD) 13.73 (5.44) 14.42 (5.88) 15.23 (3.89) 13.79 (3.48)
(μg/L) Change from baseline (Day 0) (SD) 0.70 (4.00) 0.07 (4.00)   -1.31 (3.89)
  *P value    0.207 0.104
N-telopeptide excretion Mean (SD) 36.7 (21.7) 40.1 (21.3) 34.1 (17.8) 35.1 (15.7)
nmol/mM Cr) Change from baseline (Day 0) (SD)   3.4 (12.66)   1.0 (15.97)
  *P value    0.588 0.440
OH proline excretion (nmol/mM Cr) Mean (SD) 15.5 (5.39) 17.2 (6.75) 15.5 (4.98) 15.6 (4.57)
  Change from baseline (Day 0) (SD)   1.6 (5.98)   0.1 (4.70)
  *P value    0.971 0.216
  1. *p-value comparing groups at Day 0 (italics) and for change from Day 0 to Day 84