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Table 2 Serum bone metabolic markers over the study period for spring water and magnesium bicarbonate (supplemented) spring water groups

From: A double-blind, placebo-controlled study of the short term effects of a spring water supplemented with magnesium bicarbonate on acid/base balance, bone metabolism and cardiovascular risk factors in postmenopausal women

  

Spring Water (n = 33)

Supplemented Spring Water (n = 34)

 

Visit

Day 0

Day 84

Day 0

Day 84

Parathyroid Hormone (pmol/L)

Mean (SD)

3.85 (1.79)

4.57 (2.14)

4.24 (1.74)

4.21 (1.96)

 

Change from baseline (Day 0) (SD)

 

0.72 (1.52)

 

-0.02 (1.65)

 

*P value

  

0.369

0.059

1,25dihydroxyvitamin D (pmol/L)

Mean (SD)

120.8 (40.9)

126.8 (40.4)

118.7 (39.8)

124.3 (40.7)

 

Change from baseline (Day 0) (SD)

 

7.1 (49.1)

 

5.6 (47.9)

 

*P value

  

0.835

0.766

Osteocalcin

Mean (SD)

13.73 (5.44)

14.42 (5.88)

15.23 (3.89)

13.79 (3.48)

(μg/L)

Change from baseline (Day 0) (SD)

0.70 (4.00)

0.07 (4.00)

 

-1.31 (3.89)

 

*P value

  

0.207

0.104

N-telopeptide excretion

Mean (SD)

36.7 (21.7)

40.1 (21.3)

34.1 (17.8)

35.1 (15.7)

nmol/mM Cr)

Change from baseline (Day 0) (SD)

 

3.4 (12.66)

 

1.0 (15.97)

 

*P value

  

0.588

0.440

OH proline excretion (nmol/mM Cr)

Mean (SD)

15.5 (5.39)

17.2 (6.75)

15.5 (4.98)

15.6 (4.57)

 

Change from baseline (Day 0) (SD)

 

1.6 (5.98)

 

0.1 (4.70)

 

*P value

  

0.971

0.216

  1. *p-value comparing groups at Day 0 (italics) and for change from Day 0 to Day 84