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Table 4 Distribution of maternal serum free β-hCG and PAPP-A MoM values, according to gestational age

From: The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

   Free β-hCG MoM    PAPP-A MoM  
Group Week of gestation Median Mean
log10
SD
log10
CV*
(%)
Median Mean
log10
SD
log10
CV*
(%)
1 10 to 10+6/7 1.04 -0.0655 0.2494 0.04 0.99 0.0043 0.2398 0.55
2 11 to 11+6/7 0.98 0.0294 0.2651 0.09 0.98 -0.0177 0.2204 0.12
3 12 to 12+6/7 0.99 0.0334 0.2619 0.08 0.99 0.0170 0.2335 0.14
4 13 to 13+6/7 1.03 0.0294 0.2637 0.09 1.02 0.0453 0.2290 0.05
  Total 1.00 0.0067 0.2600 - 0.98 0.0122 0.2307 -
  1. Gaussian distribution was confirmed by Kolgomorov-Smirnov test for normality
  2. MoM - Multiples of the Median
  3. CV* - coefficient of variation