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Table 5 Variability of log10 MoM values of free β-hCG and PAPP-A between particular weeks

From: The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

   Free β-hCG   PAPP-A
Between-weeks' difference Sample
size
F-ratio Significance
level
F-ratio Significance
level
Group 1 vs. Group 2 (10+0 to 11+6) 949 9.221 p = 0.002* 0.191 p = 0.294
Group 2 vs. Group 3 (11+0 to 12+6) 2179 0.0372 p = 0.847 7.445 p = 0.006*
Group 3 vs. Group 4 (12+0 to 13+6) 1934 0.947 p = 0.331 8.942 p = 0.003*
All 2883 3.516 p = 0.015* 8.696 p < 0.001*
  1. * Statistically significant (one-way analysis of variance)