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Table 5 Variability of log10 MoM values of free β-hCG and PAPP-A between particular weeks

From: The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

  

Free β-hCG

 

PAPP-A

Between-weeks' difference

Sample

size

F-ratio

Significance

level

F-ratio

Significance

level

Group 1 vs. Group 2 (10+0 to 11+6)

949

9.221

p = 0.002*

0.191

p = 0.294

Group 2 vs. Group 3 (11+0 to 12+6)

2179

0.0372

p = 0.847

7.445

p = 0.006*

Group 3 vs. Group 4 (12+0 to 13+6)

1934

0.947

p = 0.331

8.942

p = 0.003*

All

2883

3.516

p = 0.015*

8.696

p < 0.001*

  1. * Statistically significant (one-way analysis of variance)