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Table 1 Gene expression of c-Fos and Egr-1 accessed using RT-PCR

From: Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slices

Conditions

c-Fos

Egr-1

 

Fold change

P value

Fold change

P value

Propofol

1.78 ± 0.17

 

0.09 ± 0.04

 

Propofol + RAS inhibitor

0.51 ± 0.12

0.024

0.62 ± 0.09

0.046

Propofol + RAF inhibitor

0.77 ± 0.08

0.041

0.67 ± 0.14

0.032

Propofol + MEK inhibitor

0.74 ± 0.10

0.036

0.49 ± 0.09

0.029

Propofol + ERK inhibitor

0.66 ± 0.11

0.032

0.59 ± 0.08

0.044

Propofol + MAPK inhibitor

0.62 ± 0.13

0.021

0.55 ± 0.14

0.037