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Figure 5 | BMC Research Notes

Figure 5

From: Expression of the transcription factor, TFII-I, during post-implantation mouse embryonic development

Figure 5

Expression of TFII-I in multiple tissues at E15 and E16. A. Skin and hair follicles, B. Submandibular gland, C. Dermis (E16), D. Gut Vill (E16), E-F. Skin and hair follicles and submandibular gland lacking immunoreactivity after pre-incubation of antibody with peptide. TFII-I expression is present in multiple tissues at ED15 and the immunoreactivity is completely competed by cognate peptide. TFII-I is expressed in skin and hair follicles (A) and in submandibular glands (B). Dermis demonstrates extensive immunoreactivity both in the superficial dermal layers and in underlying mesenchyme and vessels. TFII-I immunoreactivity is prominent in nucleus as well as cytoplasm in the dermis. D. Gut villi show both cytoplasmic and nuclear immunoreactivity particularly at the apical surface. Again, immunoreactivity is competed completely by pre-incubation of the antibody with peptide (E-F). Inset in Figure 5D shows nuclear and cytoplasmic locatization of TFII-I under 100 × magnification (Zeiss Axioscop, obj. Apochromat 100 ×). White arrows indicate positive reaction of specific antibody with TFII-I. Abbr.: De-Dermis, ED - Epidermis, GV-Gut Villi, SG-Submandibular Gland, VE - Vascular Endothelium

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