Table 1 TFII-I expression during organogenesis, as detected by IHC. Developing organs and tissues were identified using EMAGE gene expression database [12] and [25]
From: Expression of the transcription factor, TFII-I, during post-implantation mouse embryonic development
DEVELOPMENTAL STAGE | ORGAN | LOCALIZATION |
|---|---|---|
ED8.0 Embryo, Trophoectodermal derivatives | Neural ectoderm, mesoderm | Cytoplasmic (Fig. 1) |
ED9.0 Embryo: | Neural tube (brain region) Inner and outer retinal layer Eye primordium | Nuclear, cytoplasmic (Fig. 2) |
ED11 Embryo | Liver: developing hepatocytes Vasculature: lining endothelial cells Nasopharynx | Nuclear, cytoplasmic (Fig. 3A) |
ED12 Embryo | Brain Nasopharynx Heart Lung buds: developing airway epithelium, endothelial cells | Nuclear, cytoplasmic (Fig. 2E) Cytoplasmic (Fig. 2G) Cytoplasmic (Fig. 4A) Nuclear, cytoplasmic (Fig. 4B, E, 4C) |
ED15 Embryo | Skin and hair follicles Submandibular gland Lung: epithelium, endothelial cells | Cytoplasmic (Fig. 5A) Nuclear (Fig. 5B) Nuclear, cytoplasmic (Fig. 4E) |
ED16 Embryo | Dermis: superficial dermal layers, underlying mesenchyme, blood vessels Gut: villi Lung: airway epithelium, vascular endothelial cells, developing alveolar epithelium | Nuclear, cytoplasmic (Fig. 5A) Nuclear, cytoplasmic (Fig. 5D) Nuclear (Fig. 4C) |