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Figure 7 | BMC Research Notes

Figure 7

From: Alpha-santalol, a chemopreventive agent against skin cancer, causes G2/M cell cycle arrest in both p53-mutated human epidermoid carcinoma A431 cells and p53 wild-type human melanoma UACC-62 cells

Figure 7

Effects of α-santalol on p21 and p53 in UACC-62 cells. (A). Protein levels of p21 and p53 after α-santalol treatment in UACC-62 cells were evaluated by Western blotting. Cell cycle distribution in (B) p21 siRNA and (C) p53 siRNA transfected UACC-62 cells was analyzed by flow cytometer. Data were summarized and presented as the mean ± SD of three observations. For each p21 siRNA or p53 siRNA transfection in UACC-62 cells, Western blotting was performed to ensure the inhibition of p21 or p53 protein expressions.

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