Figure 1

Sex-biased and bloodmeal-induced gene expression in Aedes aegypti. A- Representation of sex-biased gene expression in adult Ae. aegypti. A total of 5,081 (32%) transcripts are accumulated at different levels (p-values < 0.001) between males (M) and non blood-fed females (NBF) (M> NBF, 2557 transcripts and NBF > M, 2524 transcripts), while 11,141 (M = NBF, 68%) did not show significant difference in accumulation between the two sexes. B- Numbers of Ae. aegypti transcripts up- or down-regulated significantly (p-values < 0.001) in females at 3, 12, 24, 48, 72, and 96 hours post bloodmeal (PBM). A total of 4,773 (30%) transcripts were found to vary in accumulation in females following a blood meal. The numbers of varying transcripts were calculated by comparison of each sample with four-day old non blood-fed females and depicted separately as up-regulated (red) and down-regulated (blue). A Bayesian t-test was performed to calculate p-values using the statistical analysis package Cyber-T at http://cybert.microarray.ics.uci.edu/.