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Table 1 Comparison of nested PCR and 2-tier serology in detection of Lyme disease among 333 patients referred by private practitioners from offices

From: Early Lyme disease with spirochetemia - diagnosed by DNA sequencing

 

Two-tier Serology

Total

 

+

-

 

Nested PCR +

0

0

0

Nested PCR -

28

305

333

Total

28

305

333

  1. + = positive
  2. - = negative
  3. Laboratory detection of Lyme disease among 333 patients referred from private offices:
  4. Confirmed case prevalence = 28/333 = 8.4% (2-tier serology only)
  5. Sensitivity of nested PCR = 0% (0/28)
  6. Sensitivity of 2-tier seropositivity = 100% (28/28)
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BMC Research Notes

ISSN: 1756-0500

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