Figure 1

Graphical outputs provided by the EMA package for the class comparison study of [18]. (a) Histogram of probesets expression values across the 23 samples after GCRMA normalisation and log2 transformation. Probesets with an expression value below 3.5 (red vertical line) are discarded. (b) Individuals factor map produced by the PCA performed on the 23 filtered gene expression profiles. (c) Heatmap of the 23 gene expression profiles based on the 100 genes with the highest interquartile range (IQR) values. Sample clustering was performed using Pearson's correlation coefficient and Ward criterion. Gene clustering was performed using absolute Pearson's correlation coefficient and Ward criterion. (d) Qqplot produced by the SAM analysis on the two groups of tumours. Probesets in green are considered to be differentially expressed between the two conditions.