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Table 5 Cox Proportional Hazards Model of Overall Survival for patients with local disease:

From: Breast cancer in moroccan young women: a retrospective study

 

Univariate analysis

 

Multivariate analysis

 
 

Hazard ratio

95% CI

P-value

Hazard ratio

95% CI

P-value

Family history

      

No

1.00

  

1.00

  

Yes

1.10

0.47 - 2.58

0.83

1.12

0.44-2.88

0.81

SBR grading

SBR I

1.00

  

1.00

  

SBR II

2.01

0.27 - 14.6

0.49

1.26

0.15-10.9

0.83

SBR III

2.55

0.35 - 18.69

0.36

1.03

0.12-8.76

0.97

Tumor size

T1

1.00

  

1.00

  

T2

1.54

0.65 - 3.66

0.33

2.25

0.50-10.19

0.30

T3

1.55

0.59 - 4.1

0.38

2.50

0.47-13.42

0.29

T4

1.64

0.64 - 4.23

0. 31

2.34

0.44-12.44

0.32

N statut

N-

1.00

  

1.00

  

N+

0.78

0.47 - 1.28

0.32

0.62

0.29-1.30

0.20

Stage

   

I

1.00

  

1.00

  

II

2.10

0.53 - 8.37

0.29

1.43

0.24-8.57

0.69

III

4.24

1.1 - 16.28

0.03

3.56

0.65-19.57

0.14

ER

ER positive

1.00

  

1.00

  

ER negative

2.25

1.37 - 3.72

0.001

2.54

1.32- 4.90

0.005

Adjuvant chemotherapy

No

1.00

  

1.00

  

Yes

0.49

0.24 - 0.99

0.04

0.74

0.18-3.05

0.68

Adjuvant hormonotherapy

No

1.00

  

1.00

  

Yes

0.45

0.28 - 0.73

0.001

0.89

0.45-1.77

0.74

Surgery type

Radical mastectomy

1.00

  

1.00

  

Conserving surgery

0.64

0. 34 - 1.23

0.17

0.50

0.19-1.18

0.11

Adjuvant radiotherapy

No

1.00

  

1.00

  

Yes

0.42

0.24-0.74

0.003

0.74

0.25-2.23

0.60

  1. 1. Reference; ER. estrogen receptors; N. lymph node; CI. confidence interval; OS. overall survival; EFS. Events free survival.