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Table 4 Average cost classified by cost composition, patient characteristics, and hospitals (US$ at 2005 prices)

From: Economic burden of beta-thalassemia/Hb E and beta-thalassemia major in Thai children

Category Direct medical cost Direct Indirect Total
  Study site Other Total non Cost  
  DFO Other drugs Medical material Blood transfusion Investigation Routine service* Operation Total Facilities   medical cost   
Hospital              
   Saraburi (N = 72) 15.52 6.53 3.60 50.99 49.99 53.27 12.95 192.84 32.06 224.90 56.81 98.39 380.09
   Phramongkutklao (N = 42) 424.91 12.38 25.97 134.91 104.11 59.78 - 762.05 20.65 782.70 181.97 241.56 1206.23
   Chulalongkorn (N = 87) 245.18 12.28 79.02 139.42 85.19 91.14 - 650.23 85.96 736.19 228.77 332.42 1297.38
   Disease type              
   Beta-thal/Hb E (N = 183) 179.05 9.53 39.59 99.18 73.33 69.35 4.01 474.04 57.78 531.82 146.09 224.19 902.10
   Homozygous beta-thal (N = 18) 408.54 17.45 54.44 184.25 109.14 87.96 11.05 872.82 4.42 877.24 272.37 284.66 1434.27
   Severity              
   Severe (N = 94) 265.15 14.13 41.35 136.11 92.12 94.98 7.80 651.63 23.32 674.95 155.53 192.53 1023.01
   Nonsevere (N = 106) 143.36 6.89 40.92 81.81 63.42 50.42 1.88 388.70 76.45 465.15 158.97 264.65 888.77
Ferritin level              
   ≤ 2,500 ng/ml (N = 77) 232.36 8.72 51.65 130.50 91.76 68.83 2.58 586.40 58.41 644.81 200.01 301.38 1146.20
   > 2,500 ng/ml (N = 50) 434.26 19.63 73.00 158.19 110.76 114.85 - 910.68 6.10 916.78 222.36 257.55 1396.69
   Complications              
   Yes (N = 18) 513.07 17.83 32.59 151.57 120.23 88.86 11.05 935.18 7.25 942.43 185.54 257.87 1385.84
   No (N = 183) 168.77 9.50 41.74 102.39 72.24 69.27 4008.00 467.91 57.50 525.41 154.63 226.82 906.86
Total              
   Mean 199.60 10.24 40.92 106.80 76.53 71.02 4.64 509.75 53.00 562.76 157.39 229.60 949.75
   Standard Deviation (SD) 364.92 14.78 72.76 83.33 50.83 95.36 33.69 547.04 247.80 606.10 201.84 520.36 n/a
   Median 0.00 3.56 12.99 109.40 77.08 63.65 0.00 323.71 0.00 362.66 92.99 67.81 654.19
   95%CI              
Lower 148.85 8.19 30.80 95.21 69.46 57.76 -0.05 433.67 18.54 478.46 129.32 157.23 806.48
Upper 250.36 12.30 51.04 118.39 83.60 84.28 9.33 585.84 87.47 647.06 185.47 301.98 1093.03
   % (subtotal) 39.16 2.01 8.03 20.95 15.01 13.93 0.91 100.00      
   % (total)           59.25 16.57 24.17 100.00
  1. *Cost of routine service covers cost of outpatient visits and inpatient services. These costs include consultation fee and overhead cost.
  2. (see Additional file 2)