Table 1 Clinical characteristics of patients
From: Alpha-1-acid glycoprotein as potential biomarker for alpha-fetoprotein-low hepatocellular carcinoma
Variable | Control (n= 96) | HCC (n= 124) | P-value (vs. control) | |||
|---|---|---|---|---|---|---|
Chronic Hepatitis ( n = 49) | Cirrhosis ( n = 47) | AFP ≤ 20 ng/mL ( n = 61) | AFP > 20 ng/mL ( n = 63) | AFP-Low HCC | AFP-high HCC | |
Age | 42.4 ± 14.9 | 53.8 ± 9.2 | 55.8 ± 14.6 | 53.5 ± 12.9 | 0.0008 | 0.0127 |
Gender (M:F) | 25:24 | 31:16 | 41:20 | 51:12 | 0.2659 | 0.0030 |
Etiology (%) | 0.0124 | 0.2458 | ||||
HBV | 69.4 | 48.9 | 47.5 | 66.7 | ||
HCV | 30.6 | 36.2 | 19.7 | 28.6 | ||
Non HBV-non-HCV | 0 | 14.9 | 32.8 | 4.8 | ||
AST (IU/mL) | 32.5 (12-194) | 42 (16-110) | 91 (5-714) | 138 (9-945) | 0.0026 | < 0.0001 |
ALT (IU/mL) | 32.5 (6-868) | 32 (15-63) | 46 (8-363) | 65 (6-347) | < 0.0001 | < 0.0001 |