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Table 2 Summary of clinical data in subgroups of CD patients with a T allele for rs4988235

From: Genetic adult lactase persistence is associated with risk of Crohn's Disease in a New Zealand population

 

N (%)

OR (95% CI)

p

Age at first diagnosis

   

   0-16 years

30 (10.6)

0.98 (0.55-1.75)

1.00

   17-40 years

203 (71.5)

1.36 (1.05-1.76)

0.021

   > 40 years

51 (18.0)

1.56 (0.96-2.53)

0.087

CD location

   

   Ileal

97 (36.5)

1.50 (1.05-2.15)

0.032

   Colonic

86 (32.3)

1.26 (0.88-1.81)

0.245

   Ileocolonic

83 (31.2)

1.25 (0.86-1.81)

0.273

CD Behaviour

   

   Inflammatory

152 (57.6)

1.36 (1.02-1.82)

0.039

   Stricturing

81 (30.7)

1.27 (0.87-1.85)

0.233

   Penetrating

31 (11.7)

1.41 (0.77-2.57)

0.315

Relative with IBD

88 (28.4)

1.71 (1.17-2.51)

0.006

Bowel resection

98 (31.6)

1.47 (1.03-2.10)

0.033

Extra Intestinal Manifestations

44 (14.2)

1.38 (0.84-2.28)

0.228

Smoker at diagnosis

CD: 112 (46.9)

Control: 130 (31.7)

1.04 (0.69-1.56)

0.918

  1. *IBD - Inflammatory Bowel Disease