Figure 1
A) Schematic drawing of the CagA EPIYA motifs detected in our clinical samples and its approximate sizes in bp (including the M13- and T7-sequence tags. B) Size distribution of the cagA EPIYA motif amplicons derived from MDA-DNA of eleven gastritis biopsy specimens (No. 6, 9, 12, 14, 18, 21, 22, 23, 25, 27, and 28). J99, 26695, and 43509 indicate the position of cagA EPIYA motif amplicons derived from H. pylori J99, 26695, and ATCC 43509T DNA, respectively. A virtual size reference marker is indicated in the left margin and a reference marker for the different EPIYA motif sizes is indicated in the right margin. C) Representative electropherograms revealing the presence of a single (cagA EPIYA-AB; No. 6) or two different (cagA EPIYA-AB and EPIYA-ABC; No. 27) cagA EPIYA motifs, indicating the presence of either one or two isogenic H. pylori strains in the same biopsy specimen. 15 and 3000 indicate the position of lower and upper size markers.