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Table 3 Chi square test results for the genotype distribution and allele frequencies of the 19- and 21-repeat alleles in elderly and control groups.

From: A microsatellite polymorphism in IGF1 gene promoter and longevity in a Han Chinese population

  All Women Men
  Elderly(%) Control(%) P value Elderly(%) Control(%) P value Elderly(%) Control(%) P value
Genotype          
19-repeat1    0.543    0.582    0.283
19/192 69(14.00) 70(16.47) 0.297 36(14.94) 33(14.80) 0.966 33(13.10) 37(18.32) 0.126
19/non2 242(49.09) 198(46.59) 0.45 126(52.28) 107(47.98) 0.355 116(46.03) 91(45.05) 0.835
non/non2 182(36.92) 157(36.94) 0.994 79(32.78) 83(37.22) 0.316 103(40.87) 74(36.63) 0.357
Allele          
19-repeat3 380(38.54) 338(39.76) 0.592 198(41.08) 173(38.79) 0.477 182(36.11) 165(40.84) 0.145
non 606(61.46) 512(60.24)   284(58.92) 273(61.21)   322(63.89) 239(59.16)  
Genotype          
21-repeat4    0.31    0.88    0.082
21/212 30(6.09) 33(7.76) 0.316 15(6.22) 16(7.17) 0.682 15(5.95) 17(8.42) 0.308
21/non2 200(40.57) 154(36.24) 0.179 94(39.00) 89(39.91) 0.842 106(42.06) 65(32.18) 0.031 6
non/non2 263(53.35) 238(56.00) 0.421 132(54.77) 118(52.91) 0.688 131(51.98) 120(59.41) 0.114
Allele          
21-repeat5 260(26.37) 220(25.88) 0.813 124(25.73) 121(27.13) 0.628 136(26.98) 99(24.50) 0.397
Non 726(73.63) 630(74.12)   358(74.27) 325(72.87)   368(73.02) 305(75.50)  
  1. 1. P values were obtained by the chi-square test of whole genotype distribution categorized by 19-repeat allele.
  2. 2. P values were obtained by the chi-square test of genotype distribution categorized by each genotype.
  3. 3. P values were obtained by the chi-square test of allele frequencies categorized by 19-repeat allele.
  4. 4. P values were obtained by the chi-square test of whole genotype distribution categorized by 21-repeat allele.
  5. 5. P values were obtained by the chi-square test of allele frequencies categorized by 21-repeat allele.
  6. 6. After Bonferroni correction, p < 0.0017 is considered significant.