Figure 2

Dissecting zebrafish development with microarray analysis. (a) Eight selected embryos ranging from the 16-cell to 8-somite stage. (b) Mean, unnormalized log₂ signal intensities from microarray analysis (smooth bars, foreground signal and scatter board bars, background signal). (c) Principal component analysis (PCA) on unnormalized log₂ ratio data (test/reference) showing a 'developmental' curve starting at the 16-cell stage and ending at the 8-somite stage. (d) Spearman correlations between the samples reflect the developmental distance.