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Table 2 Power comparison of our test and two previous tests from simulations under HWE

From: A Monte Carlo test of linkage disequilibrium for single nucleotide polymorphisms

 

α= 0.05

α= 0.01

α= 0.001

D '

our test

comp-LD

asym-LD

our test

comp-LD

asym-LD

our test

comp-LD

asym-LD

0

0.0500

0.0540

0.052

0.0100

0.0103

0.0105

0.0010

0.0011

0.0011

0.025

0.1232

0.1209

0.1201

0.0356

0.0324

0.0316

0.0059

0.0052

0.0048

0.05

0.3504

0.3468

0.3452

0.1564

0.1467

0.1455

0.0429

0.0386

0.0372

0.075

0.6696

0.6656

0.6643

0.4238

0.4095

0.4081

0.1810

0.1706

0.1659

0.1

0.8895

0.8847

0.8803

0.7200

0.7083

0.7051

0.4474

0.4325

0.4188

0.125

0.9814

0.9794

0.9726

0.9243

0.9218

0.9194

0.7598

0.7500

0.7259

0.15

0.9982

0.9979

0.9939

0.9875

0.9873

0.9869

0.9319

0.9301

0.9286

0.175

0.9998

0.9996

0.9992

0.9978

0.9975

0.9969

0.9875

0.9868

0.9856

0.2

1.0000

1.0000

1.0000

0.9999

0.9999

0.9997

0.9990

0.9988

0.9987

0.225

1.0000

1.0000

1.0000

1.0000

1.0000

1.0000

0.9998

0.9997

0.9995

0.25

1.0000

1.0000

1.0000

1.0000

1.0000

1.0000

1.0000

1.0000

1.0000

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BMC Research Notes

ISSN: 1756-0500

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