Table 3 Power comparison of our test and two previous tests from simulations under HWD
From: A Monte Carlo test of linkage disequilibrium for single nucleotide polymorphisms
α= 0.05 | α= 0.01 | α= 0.001 | |||||||
|---|---|---|---|---|---|---|---|---|---|
D ' | our test | comp-LD | asym-LD | our test | comp-LD | asym-LD | our test | comp-LD | asym-LD |
0 | 0.0500 | 0.0505 | 0.0503 | 0.0100 | 0.0102 | 0.0103 | 0.0010 | 0.0013 | 0.0012 |
0.025 | 0.1538 | 0.1523 | 0.1519 | 0.0553 | 0.0516 | 0.0508 | 0.0122 | 0.0093 | 0.0088 |
0.05 | 0.4643 | 0.4642 | 0.4638 | 0.2480 | 0.2372 | 0.2366 | 0.0888 | 0.0752 | 0.0732 |
0.075 | 0.8006 | 0.8000 | 0.7897 | 0.5984 | 0.5858 | 0.5836 | 0.3388 | 0.3057 | 0.3021 |
0.1 | 0.9612 | 0.9610 | 0.9607 | 0.8838 | 0.8783 | 0.8779 | 0.7047 | 0.6728 | 0.6705 |
0.125 | 0.9958 | 0.9957 | 0.9952 | 0.9811 | 0.9799 | 0.9781 | 0.9267 | 0.9119 | 0.9106 |
0.15 | 0.9999 | 0.9999 | 9.9998 | 0.9987 | 0.9984 | 9.9981 | 0.9912 | 0.9899 | 0.9883 |
0.175 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.9998 | 0.9997 | 0.9995 |
0.2 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.225 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.25 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |