Figure 1

Functional expression of receptors in X. oocytes microinjected with plasma membranes. The current responses were recorded 24 hours after microtransplantation. A. GABA and glutamate responses in X. oocytes microinjected with mouse brain tissue. B. Responses from mouse respiratory epithelium to the odorant heptanal, the CFTR activator IBMX and the β2 adrenergic agonist, isoproterenol. C. Responses from mouse olfactory epithelial preparations to heptanal and IBMX. The response to 100 μM heptanal indicates specific responses from olfactory receptors, since it is absent from respiratory epithelium (B). Similar results were obtained from 10-12 oocytes tested.