Figure 1

Data plots for assessing differentially expressed genes in quiescent Balb/c 3T3 cells after E1A induction. The left panel represents a Shrinkage Plot where every point represents a gene. Red dots and green dots indicate genes that were up regulated and down regulated, respectively, while the blue dots represent those genes that were non-regulated. The horizontal axis shows BAM Zcut values of expression changes while the vertical axis shows the corresponding Posterior Variances. The right panel is a diagnostic volcano plot of the comparison between quiescent Balb/c 3T3 cells with or without the expression of E1A. In this plot, each individual gene is arranged by statistical significance, and the most significant of these are those that have the largest estimated magnitude of change (i.e. Group Mean Difference) and the largest absolute value t-test (distributed in the top right or left of the plots). The genes that were significantly up regulated are highlighted in red, and those that were significantly down regulated are highlighted in green.