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Table 4 Result of biomarkers in exhaled air, taking asthma severity into account

From: Analysis of nitrogen oxides (NOx) in the exhaled breath condensate (EBC) of subjects with asthma as a complement to exhaled nitric oxide (FeNO) measurements: a cross-sectional study

 

GINA4 (n = 12)

GINA3 (n = 11)

Controls (n = 23)

Statistics1

FeNO50 a

32.6 [16.8 - 70.9]

27.6 [18.1 - 42.3]

9.6 [8.4 - 14.2]

< 0.001 §,£

CalvNO (ppb) a

2.8 [2.0 - 2.8]

4.4 [2.9 - 6.6]

1.7 [1.1 - 2.8]

0.003 §

J'awNO (nL/min) a

79.0 [44.3 - 175.4]

81.6 [58.5 - 114.4]

30.9 [25.7 - 46.3]

0.005 §,£

NOx (μM) a

12.5 [9.0 - 19.5]

16.9 [14.0 - 19.7]

9.9 [7.5 - 15.0]

0.074

  1. FeNO50: Fractional exhaled nitric oxide at 50mL/s, CalvNO: Alveolar NO concentration, J'awNO: Bronchial NO concentration, NOx: Oxides of nitrogen
  2. a data expressed as geometric mean [IQR]
  3. 1 ANOVA
  4. § Significant increase GINA 3 vs controls
  5. £ Significant increase GINA 4 vs controls