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Table 4 Result of biomarkers in exhaled air, taking asthma severity into account

From: Analysis of nitrogen oxides (NOx) in the exhaled breath condensate (EBC) of subjects with asthma as a complement to exhaled nitric oxide (FeNO) measurements: a cross-sectional study

  GINA4 (n = 12) GINA3 (n = 11) Controls (n = 23) Statistics1
FeNO50 a 32.6 [16.8 - 70.9] 27.6 [18.1 - 42.3] 9.6 [8.4 - 14.2] < 0.001 §,£
CalvNO (ppb) a 2.8 [2.0 - 2.8] 4.4 [2.9 - 6.6] 1.7 [1.1 - 2.8] 0.003 §
J'awNO (nL/min) a 79.0 [44.3 - 175.4] 81.6 [58.5 - 114.4] 30.9 [25.7 - 46.3] 0.005 §,£
NOx (μM) a 12.5 [9.0 - 19.5] 16.9 [14.0 - 19.7] 9.9 [7.5 - 15.0] 0.074
  1. FeNO50: Fractional exhaled nitric oxide at 50mL/s, CalvNO: Alveolar NO concentration, J'awNO: Bronchial NO concentration, NOx: Oxides of nitrogen
  2. a data expressed as geometric mean [IQR]
  3. 1 ANOVA
  4. § Significant increase GINA 3 vs controls
  5. £ Significant increase GINA 4 vs controls