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Table 2 Performance of various modules of SVM developed by using Amino acid, dipeptide, split (2 and 4-part), PSSM and PSSM-PROSITE domain based input features

From: Analysis and prediction of cancerlectins using evolutionary and domain information

Methods

Threshold

Sensitivity

Specificity

Accuracy

MCC

Amino acid Composition

-0.3

67.97

64.15

65.84

0.32

Dipeptide Composition

-0.3

67.27

62.84

64.84

0.30

Split based Composition (2-part)

-0.3

66.32

64.18

65.10

0.31

Split based Composition (4-part)

-0.5

65.12

66.85

66.09

0.32

Position-Specific Scoring Matrix

-0.2

67.92

68.57

68.34

0.36

PSSM with 14 PROSITE domains

-0.1

68.00

69.90

69.09

0.38

  1. (For details see Additional file 1 Tables S3 to S8)