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Table 1 LC viability after treatment with immunomodulatory drugsa

From: Effects of immunomodulatory drugs on TNF-α and IL-12 production by purified epidermal langerhans cells and peritoneal macrophages

 

Concentration

Viability (%)

Freshly isolated LC

-

94.4 ± 2.1

36 h cultured LC

-

73.3 ± 2.8

Prednisone

10-6 M

69.9 ± 3.7

 

10-8 M

66.7 ± 5.5

Thalidomide

10-6 M

63.5 ± 3.2

 

10-8 M

61.4 ± 2.1

Cyclosporine A

10-6 M

62.2 ± 6.4

 

10-8 M

61.2 ± 10.7

Amitriptyline

10-6 M

66.2 ± 2.2

 

10-8 M

64.6 ± 1.7

  1. aPurified LC were cultured for 36 h in the presence or absence of 10-6 M or 10-8 M prednisone, thalidomide, cyclosporine A, or amitriptyline. Cell viability was then assessed using propidium iodide. All results are shown as mean ± SD for three independent experiments, which did not vary significantly from the control.
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BMC Research Notes

ISSN: 1756-0500

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