| |
Concentration
|
Viability (%)
|
|---|
|
36 h cultured Mϕ
|
-
|
95.8 ± 1.5
|
|
Prednisone
|
10-6 M
|
84.2 ± 2.5
|
| |
10-8 M
|
86.1 ± 1.7
|
|
Thalidomide
|
10-6 M
|
85.4 ± 3.2
|
| |
10-8 M
|
86.9 ± 2.2
|
|
Cyclosporine A
|
10-6 M
|
85.5 ± 2.3
|
| |
10-8 M
|
88.2 ± 3.7
|
|
Amitriptyline
|
10-6 M
|
83.8 ± 2.9
|
| |
10-8 M
|
87.7 ± 0.8
|
- aPurified MΦ were first pre-incubated for 24 h with 10 ng/ml LPS, and then cultured for 36 h in the presence or absence of 10-6 M or 10-8 M prednisone, thalidomide, cyclosporine A, or amitriptyline. Cell viability was then assessed using propidium iodide. All results are shown as mean ± SD for three independent experiments, which did not vary significantly from the control.
