Figure 1

Effect of amino acid exchange polymorphisms on CoQ 10 plasma levels. SNPs in genes encoding enzymes of the CoQ10 synthesis pathway (CoQ3G272S, CoQ6M406V, CoQ7M103T) before (T0) and after (T14) ubiquinol supplementation (150 mg/day) in humans are shown. Values are mean ± SD and n numbers (genotype distribution) are given in brackets. Differences between two genotype groups were examined using Student t-test and between all genotypes using "test for linear trend" (ANOVA).