Figure 10From: Structure-Function Analysis of Diacylglycerol Acyltransferase Sequences from 70 OrganismsSequence analysis of important amino acid residues in less conservative regions of DGAT2s. (A) YFP motif (The boxed Y, F and P residues are mutated in baker's yeast DGAT2 corresponding to Y129/F130/P131), (B) The boxed F, L and L residues are mutated in mouse DGAT2 corresponding to F80, L81 and L83 and in baker's yeast DGAT2 corresponding to F71 and L73, (C) The boxed C residue is mutated in baker's yeast DGAT2 corresponding to C314. Multiple sequence alignment was performed using 54 full-length DGAT2 protein sequences from 44 organisms (listed in Table 1). Color code and related information are described briefly in Figure 2 legend and with details in "Methods" section. The amino acid residues studied by mutagenesis and the corresponding conserved residues in other organisms are boxed within the sequence alignment.Back to article page