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Figure 10 | BMC Research Notes

Figure 10

From: Structure-Function Analysis of Diacylglycerol Acyltransferase Sequences from 70 Organisms

Figure 10

Sequence analysis of important amino acid residues in less conservative regions of DGAT2s. (A) YFP motif (The boxed Y, F and P residues are mutated in baker's yeast DGAT2 corresponding to Y129/F130/P131), (B) The boxed F, L and L residues are mutated in mouse DGAT2 corresponding to F80, L81 and L83 and in baker's yeast DGAT2 corresponding to F71 and L73, (C) The boxed C residue is mutated in baker's yeast DGAT2 corresponding to C314. Multiple sequence alignment was performed using 54 full-length DGAT2 protein sequences from 44 organisms (listed in Table 1). Color code and related information are described briefly in Figure 2 legend and with details in "Methods" section. The amino acid residues studied by mutagenesis and the corresponding conserved residues in other organisms are boxed within the sequence alignment.

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