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Table 1 Patient characteristics by self-reported hypoglycemic symptoms

From: Assessment of severity and frequency of self-reported hypoglycemia on quality of life in patients with type 2 diabetes treated with oral antihyperglycemic agents: A survey study

Characteristic

All Patients

With Hypoglycemic Symptoms

Without Hypoglycemic Symptoms

p-value

 

N = 1984

n = 1248 (63%)

n = 736 (37%)

 

Female (%)

43

47

37

<.0001§

Male (%)

57

53

63

 

Age, years

58.1 ± 11.1

56.8 ± 11.2

60.4 ± 10.4

<.0001‡

Body mass index, kg/m2

34.5 ± 8.2

34.8 ± 8.4

34.0 ± 7.9

0.0229‡

Duration of diabetes, years

7.3 ± 6.4*

7.2 ± 6.2

7.5 ± 6.6

0.2737‡

HbA1c <7%† (%)

72.2

71.4

73.6

0.3667§

Any weight gain (%)

36.9

41.5

29.1

<.0001§

   Amount of weight gain

<10 lbs (%)

27.9

25.9

32.7

 

10-20 lbs (%)

47.5

48.7

44.9

<.0001¶

21-30 lbs (%)

12.3

12.6

11.7

 

>30 lbs (%)

12.3

12.9

10.8

 

Microvascular (%)

22.5

25.8

16.9

<.0001§

   Macular edema (%)

4.0

4.8

2.6

0.0143§

   Kidney disease (%)

2.5

2.9

1.8

0.1210§

   Foot or leg ulcer (%)

3.6

4.2

2.6

0.0663§

   Neuropathic pain (%)

17.3

20.4

12.1

<.0001§

Selected cardiovascular conditions (%)

19.5

21.6

15.9

0.0018§

   Angina (%)

8.5

9.9

6.3

0.0054§

   Heart attack (%)

8.0

8.2

7.7

0.7342§

   Stroke (%)

4.3

4.7

3.5

0.2042§

   Peripheral vascular disease (%)

0.96

1.0

0.82

0.6169§

   Congestive heart failure (%)

4.3

4.7

3.7

0.2983§

Current antihyperglycemic agents regimen

    

   Treatment regimen including a sulfonylurea (%)

50

55

42

<.0001¶

   All other treatment regimens (%)

50

45

58

 
  1. Data are presented as frequency and mean ± standard deviation.
  2. *median 6 yrs.; 25th percentile 3 yrs.; 75th percentile 10 yrs.
  3. †n = 1439
  4. Based on ‡ t-test, § chi-square, or ¶ Wald test of joint significance.