Study | BSE-positive cattle a N animals N recordings (female/male) | BSE-negative cattle b N animals N recordings (female/male) | Controls c N animals N recordings (female/male) |
|---|
1 | 2 (0/2) 2 (0/2) | 220 (0/220) 244 (0/244) | 9 (0/9) 9 (0/9) |
2 | 9 (5/4) 12 (8/4) | 27 (8/19) 38 (18/20) | 19 (9/10) 27 (17/10) |
3 | 14 (0/14) 38 (0/38) | 36 (0/36) 101 (0/101) | 8 (0/8) 28 (0/28) |
4 | 2 (0/2) 12 (0/12) | 1 (0/1) 27 (0/27) | 11 (0/11) 80 (0/80) |
5 | 2 (0/2) 23 (0/23) | 10 (0/10) 100 (0/100) | 12 (0/12) 238 (0/238) |
6 | 7 (2/5) 9 (2/7) | 0 | 2 (1/1) 2 (1/1) |
7 | 15 (15/0) 15 (15/0) | 27 (27/0) 29 (29/0) | 17 (18/0) 18 (17/0) |
Total
|
51 (22/29)
111 (25/86)
|
321 (35/286)
536 (46/490)
|
78 (27/51)
401 (36/365)
|
- a Cattle with BSE confirmed by postmortem tests.
- b BSE field suspects or cattle inoculated with tissue/body fluids from naturally infected BSE cases or from BSE/scrapie-challenged animals, which were not confirmed as BSE cases by postmortem tests.
- c Cattle inoculated with saline solution or BSE/scrapie-free tissue or not challenged.
- 1 Cattle intracerebrally inoculated with various tissues collected from cattle orally dosed with classical BSE brainstem homogenate and saline-inoculated controls [45, 46].
- 2 Cattle orally dosed with 1 g or 100 g classical BSE brainstem homogenate and culled at various times post challenge and undosed controls [1].
- 3 Cattle orally dosed with 1 g-1 mg classical BSE brainstem homogenate and undosed controls [7].
- 4 Cattle orally dosed with 100 g classical BSE brainstem homogenate and undosed controls as well as controls orally dosed with 100 g BSE-free brainstem homogenate sourced from New Zealand.
- 5 Cattle intracerebrally inoculated with scrapie brain homogenate, saline-inoculated controls and controls inoculated with scrapie-free brain [6] as well as cattle orally inoculated with 100 g scrapie brain homogenate and undosed controls.
- 6 Cattle intracerebrally inoculated with atypical BSE brain homogenate (L-type or H-type BSE) as well as unchallenged controls.
- 7 BSE suspects reported by the farmer and healthy controls purchased from farms [14].
