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Table 7 Association of heart rate and sympathovagal balance with neuropathological changes in selected nuclei of the obex

From: Time and frequency domain analysis of heart rate variability in cattle affected by bovine spongiform encephalopathy

 

Neuroanatomical area

Score

N cattle

Heart rate [bpm]

Median

(range)

P-value

LF:HF power ratio

Median

(range)

P-value

Vacuolation

Parasympathetic nucleus of the vagus nerve

0

13

59

(54-86)

ns

31.5

(5.3-164.8)

0.01

score

(neuropil*)

≥ 2

9

46

(32-76)

(0.08)

5.1

(0.5-37.5)

 
 

Solitary tract nucleus

0-1

12

61

(54-89)

ns

33.1

(5.3-87.6)

ns

 

(neuropil*)

3-4

21

64

(32-84)

(0.99)

10.2

(0.5-1831.0)

(0.15)

PrPd

Parasympathetic nucleus of the vagus nerve

0

10

69

(54-81)

ns

43.0

(2.7-164.8)

ns

intensity

(intraneuronal)

2

17

65

(39-109)

(0.90)

24.6

(1.1-1831.0)

(0.56)

score

Parasympathetic nucleus of the vagus nerve

0-1

11

66

(58-89)

ns

27.5

(6.7-146.0)

ns

 

(neuropil)

3-4

26

63

(32-109)

(0.13)

16.5

(0.5-1831.0)

(0.34)

 

Solitary tract nucleus

0-1

6

66

(55-81)

ns

27.1

(2.7-164.8)

ns

 

(neuropil*)

3-4

33

63

(32-109)

(0.63)

12.3

(0.5-1831.0)

(0.65)

  1. * Intraneuronal vacuolation in the PNV was too infrequent to be used for comparison; vacuolation and PrPd accumulation in the STN was exclusively in the neuropil.
  2. ns = not significant (P > 0.05).