From: Limited redundancy in genes regulated by Cyclin T2 and Cyclin T1
Condition | Disease/Processes | Genes |
---|---|---|
Specific to Cyclin T2 depletion | Aging | Fas (TNF receptor superfamily, member 6) |
 |  | N-acteyltransferase 1 (Arylamine N-acteyltransferase) |
 |  | ATP-binding cassette, sub-family A (ABC1), member 1 |
 |  | Superoxide dismutase 2, mitochondrial |
 |  | Hemochromatosis |
Specific to Cyclin T1 depletion | HIV-1 biology | Cyclin dependent kinase 9 (Cdk9) |
 |  | Cyclin T1 |
 |  | Granulin |
 |  | Major histocompatibility complex, Class II, DM alpha |
 |  | Tubulin, beta 6 |
 | Dementia | Amyloid beta (A4) precursor protein (peptidase Nexin-II, Alzheimer disease) |
 |  | Very low density lipoprotein receptor |
 |  | Estrogen receptor 1 |
 |  | Microtubule-associated protein (Tau) |
 |  | Serpin peptidase inhibitor, clade 1 (Neuroserpin), member 1 |
 |  | Synuclein, alpha (non A4 component of amyloid precursor) |
 | Cholesterol, LDL | Proprotein convertase Subtilisin/Kexin type 9 |
 |  | Low density lipoprotein receptor (familial hypercholesterolemia) |
 |  | Apolipoprotein C-1 |
 |  | Low density lipoprotein receptor adaptor protein 1 |
 | Gallstones | Low density lipoprotein receptor-related protein associated Protein 1 |
 |  | Low density lipoprotein receptor (familial hypercholesterolemia) |
 |  | Apolipoprotein C-1 |
 | Macular degeneration, age-related | very low density lipoprotein receptor |
 |  | Microsomal Glutathione S-transferase 1 |
 |  | Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
 | Colorectal cancer | Platelet-derived growth factor receptor-like |
 |  | V-HA-Ras Harvey rat sarcoma viral oncogene homolog |
 |  | Mutated in colorectal cancers |
 | Bladder cancer | V-HA-Ras Harvey rat sarcoma viral oncogene homolog |
 |  | Fibroblast growth factor receptor 3 ( Achondroplasia, Thanatophoric dwarfism) |
Common to Cyclin T2 and Cyclin T1 depletion | Metabolic | Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
 |  | ATPase, class 1, Type 8B, member 1 |
 |  | Heme oxygenase (decycling) 1 |
 |  | Syndecan 2 (heparin sulfate proteoglycan 1, cell surface-associated, fibroglycan) |
 |  | Bone morphogenetic protein 2 |
 |  | Calmodulin 1 (Phosphorylase kinase, delta) |
 |  | Hydatidiform mole associated and imprinted |
 |  | Scavenger receptor class B, member 1 |
 |  | Smad, mothers against DPP homolog 4 (Drosophila) |
 | Metabolic | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, psudoinflammatory) |
 |  | Fibrillin 1 (Marfan syndrome |
 | Cardiovascular | Neural precursor cell expressed, developmentally downregulated 4-like |
 |  | Cyclin dependent kinase inhibitor 1C (p57, Kip2) |
 |  | Caspase 1, Apoptosis-related Cysteine peptidase (Interleukin 1, beta, convertase) |
 |  | Heme oxygenase (decycling) 1 |
 |  | Calmodulin 1 (Phosphorylase kinase, delta) |
 |  | Poliovirus receptor-related 2 (Herpesvirus entry mediator B) |
 |  | Scavenger receptor class B, member 1 |
 |  | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, psudoinflammatory) |