Pegylated interferon-alfa-2a monotherapy in patients infected with HCV genotype 2 and importance of rapid virological response

Table 1 Demographic data of patients according to HCV RNA levels

Groups	Low Viral Load	High Viral Load	P- value
N	15	34
Age (years)	50.8 ± 14.5	53.3 ± 11.7	N.S.
Gender (male/female)	11/4	21/13	N.S.
ALT (IU/L)	71.5 ± 56.5	100 ± 76.3	N.S.
Platelets (× 10⁴/mm³)	17.4 ± 5.5	100 ± 76.3	N.S.
HCV RNA (KIU/mL)	37.5 ± 26.3	459 ± 330	< 0.0001
Duration of treatment (days)	120 ± 80	236 ± 115	N.S.
RVR/non-RVR	15/0	19/15	0.0059

Low and high viral load were defined as < 100 KIU/mL and > 100 KIU/mL, respectively. ALT, alanine aminotransferase; RVR, rapid virological response; N.S., statistically not significant. Data are shown as mean ± S.D. Statistical analysis was carried out using Student's t-test or chi-square test. P < 0.05 was considered statistically significant.

ISSN: 1756-0500